HORDB

ID: hor002638
Uniprot ID: G5EGN6
Protein name: NLP-15
Gene name: nlp-15
Organism: Caenorhabditis elegans
Family: NA
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: NA

Sequence: AFDSLAGSGFDNGFN
Length: 15(48-62)
Propeptide: MPSSSSSSSFFAAVLLVIVMMSTVESAAVRLRPVGSLFFLNRPHEKRAFDSLAGSGFDNGFNKRAFDSLAGSGFGAFNKRAFDSLAGSGFGAFNKRAFDSLAGSGFSGFDKRAFDSLAGQGFTGFEKRAFDTVSTSGFDDFKL
Signal peptide: MPSSSSSSSFFAAVLLVIVMMSTVES
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002638_AF2.pdb

hor002638_ESM.pdb

Mass:	176846	Formula:	C67H91N17O24
Absent amino acids:	CEHIKMPQRTVWY	Common amino acids:	FG
pI:	3.49	Basic residues:	0
Polar residues:	7	Hydrophobic residues:	6
Hydrophobicity:	-6.67	Boman Index:	-1722
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	39.33
Instability Index:	2860.67	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 20013198
Title: Approaches to Identify Endogenous Peptides in the Soil Nematode Caenorhabditis elegans